Research progress on mechanical and flow properties of blood cells in microcirculation using microfluidic devices

QI Xiaojing; LI Xuejin

doi:10.11729/syltlx20190158

Volume 34 Issue 2

Apr. 2020

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QI Xiaojing, LI Xuejin. Research progress on mechanical and flow properties of blood cells in microcirculation using microfluidic devices[J]. Journal of Experiments in Fluid Mechanics, 2020, 34(2): 1-10. doi: 10.11729/syltlx20190158

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Research progress on mechanical and flow properties of blood cells in microcirculation using microfluidic devices

doi: 10.11729/syltlx20190158

QI Xiaojing,
LI Xuejin^,

Institute of Fluid Engineering, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China

Received Date: 2019-11-28
Rev Recd Date: 2020-02-25
Publish Date: 2020-04-25

Abstract

Abstract

Microfluidics (or lab-on-a-chip) is an important technology suitable for a wide range of biomedical applications from single-cell analysis to point-of-care diagnosis. In this paper, we review recent advances in the applications of the microfluidic technology in the field of cell biology and biomechanics. We highlight examples of some successful applications of microfluidic devices in probing the mechanical and rheological characteristics of blood cells in healthy and diseased states at single-cell and multi-cell levels, and in investigating the cell migration and separation at the whole-cell population.
- micro/nano flow,
- blood cell,
- cell mechanics,
- cell dynamics,
- cell separation

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References(53)

References

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